Vitamin K2 plays a significant role in calcium utilization for optimal bone and heart health because it puts calcium where it is needed – into bones, not arteries. K2’s mechanism of action involves two key proteins - osteocalcin and matrix Gla protein (MGP). Osteocalcin plays a role in the integration of calcium into the bone matrix whereas MGP keeps calcium away from arteries. There’s a strong association exist between decreased bone mineral density and increased risk of both cardiovascular disease (CV) and CV death. Unfortunately, our diets today do not provide us with enough vitamin K2. Therefore, there is a need for K2 supplementation.
In fact, K2 was ‘the missing vitamin’ for a long time. The deficiency of K2 is especially manifested in people who has chronic kidney disease (CKD), dialysis, diabetes, and post-menopausal women. Emerging evidence has suggested that vitamin K together with vitamin D may confer protective effects for both skeletal and CV systems. The perfect pair, Vitamin K2 & D3 work synergistically to support the benefits of calcium for both bone health and lowers the risk of arterial calcification to maintain cardiovascular health.
Powerlife K2D3 features a combination of vitamin K2 as MK-7, sourced from patented K2VITAL®️ DELTA and vitamin D3 from Vitashine - the world’s only vegan society and vegetarian society registered Vitamin D3 which extracted from lichen. As a fat-soluble vitamin, unprotected K2 can degrade in certain environments and formulations. Vitamin K2 MK-7 is particularly susceptible to degradation in combination with minerals, notably calcium, magnesium, other harsh organic-alkaline environments. K2VITAL®️DELTA in Powerlife K2D3 utilizes double coated, microencapsulation technology that ensures Vitamin K2 stability, shelf-life and label claim under harsh environments. K2VITAL®️DELTA in Powerlife K2D3 offers the assurance of stability over two years of long-term stability testing, demonstrating minimal loss even at accelerated temperatures (25°C vs 40°C). Whilst most of the marketed Vitamin D3 is derived from sheep’s wool, Vitashine that used in Powerlife K2D3 is a special oily extract of Lichen which naturally rich in Vitamin D3 (Cholecalciferol) and fatty acids. Powerlife K2D3 offers the safest choice of vitamin D3 for vegans and vegetarians.
DELTA® Encapsulated K2 MK-7 Stability
Source : Synthetica AS © Kappa Bioscience 2017
Note: Testing standard deviation +/- 3% for 24months at 40°C
LATEST UPDATE (2021)
K2D3 potential contribution to reducing the COVID-19 mortality rate
Beneficial effect of Vitamin D on the immune system maintenance and enhancement is proven. A latest systematic review published in May 2021, Vitamin D insufficiency was present in 93.1% of the patients with severe-critical COVID-19. Vitamin D preserves tight junctions of respiratory cells, kills enveloped virus, and reduces cytokine storm risk, amongst other functions. That is how Vitamin D works. So, is Vitamin D supplementation necessary during this pandemic? Yes, if you are spending most of your time indoor, especially during the pandemic season.
Oral supplementation of D3 is the easiest means to prevent deficiencies. Yet there’s a rising concern of Vitamin D3 supplementation poses risk of hypercalcemia, a condition that causing calcium build in blood lead to vascular calcification, osteoporosis and kidney stones. To counteract on this unwanted outcome, Vitamin K2 is essential to take along with D3. K2 activates osteocalcin, K2 in here play a crucial role in depositing the calcium specifically into bones instead of soft tissues maximizing the immune protective effect of Vitamin D3 while maintaining the heart and bone health at the same time.
Prevents arterial calcification (hardening of blood vessels)
Helps maintain regular heart rhythms
Maintains elasticity of blood vessels
Reduce risk of flu and regulate immune system
Balances calcium level for better bone and cardiovascular health
Promotes stronger and healthier bones
Vitamin K2 (as MK-7) 120 mcg
Vitamin D3 1000IU
Take one capsule once daily with meal